SCHEMBL30278494

SCHEMBL30278494

Fc1ccc2[nH]cc(Cc3ccccn3)c2c1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.65
MPO P05164 12/20 0.54
HTR2A P28223 2/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
HTR1A P08908 1/20 0.50
KMT2A Q03164 1/20 0.50
TSHR P16473 1/20 0.49
HTR2C P28335 1/20 0.48
SLC6A4 P31645 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25042441 1.00 GPR84 (0.65) GPR84MPOHTR2ATRPM8HTR1A
SCHEMBL25042586 0.89 GPR84 (0.65) GPR84HTR2AHTR1AKMT2A
SCHEMBL735576 0.82 GPR84 (0.65) GPR84MPOHTR2AHTR1AKMT2A
SCHEMBL31744758 0.82 GPR84 (0.65) GPR84MPOHTR2AHTR1AKMT2A
SCHEMBL25042583 0.80 GPR84 (0.68) GPR84HTR2ATRPM8HTR1ATSHR
SCHEMBL30278550 0.80 GPR84 (0.68) GPR84HTR2ATRPM8HTR1ATSHR
SCHEMBL30913603 0.80 GPR84 (1.00) GPR84MPOHTR2ATRPM8HTR1A
SCHEMBL30482437 0.80 GPR84 (1.00) GPR84MPOHTR2ATRPM8HTR1A
SCHEMBL18383118 0.80 GPR84 (1.00) GPR84MPOHTR2ATRPM8HTR1A
SCHEMBL29007187 0.79 GPR84 (1.00) GPR84MPOHTR2ATRPM8HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023018480-A1 SELECTIVE PSYCHEDELIC COMPOUNDS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2023-02-16 WO disclosed