SCHEMBL30278500

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1476671	0.81	GRM5 (0.50)	GRM5FFAR1
	Hydrochloric Acid SCHEMBL1476841	0.78	GRM5 (0.54)	GRM5HAO1KCNH2CYP2A6CYP2E1
	SCHEMBL30278437	0.78	GRM5 (0.59)	GRM5FFAR1HAO1
	SCHEMBL12135612	0.77	ADORA1 (0.47)	GRM5NPY5RKCNH2DYRK1AKCNA5
	SCHEMBL30562384	0.76	NPY5R (0.67)	NPY5RKCNH2DYRK1AKCNA5CYP2A6
	SCHEMBL9679235	0.76	GRM5 (0.53)	GRM5FFAR1CYP3A4RAB9A
	SCHEMBL13362351	0.76	NPY5R (0.67)	NPY5RKCNH2DYRK1AKCNA5CYP2A6
	SCHEMBL2303193	0.76	NPC1 (0.51)	NPY5RGRM2KCNH2DYRK1AKCNA5
	SCHEMBL29497468	0.76	NPC1 (0.51)	NPY5RGRM2KCNH2DYRK1AKCNA5
	SCHEMBL30963881	0.76	CYP19A1 (0.50)	GRM5HAO1KCNH2CYP2A6CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.