SCHEMBL30278570

SCHEMBL30278570

O=C(O)c1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 12/20 0.69
MEN1 O00255 1/20 0.58
TTR P02766 1/20 0.58
PPOX P50336 1/20 0.58
KMT2A Q03164 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
FFAR1 O14842 3/20 0.56
KMO O15229 1/20 0.55
NR4A2 P43354 1/20 0.53
AKR1C3 P42330 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791436 1.00 MRGPRX4 (0.69) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL10687740 0.90 MRGPRX4 (0.66) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL8015966 0.90 MRGPRX4 (0.54) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL8602322 0.90 KMO (0.58) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL8011544 0.88 MRGPRX4 (0.65) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL10613595 0.88 MAOB (0.55) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL7574658 0.87 MRGPRX4 (0.53) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL11113346 0.87 MRGPRX4 (0.53) MRGPRX4MEN1TTRPPOXKMT2A
Potassium Ion SCHEMBL27878046 0.87 MRGPRX4 (0.53) MRGPRX4MEN1TTRPPOXKMT2A
SCHEMBL10673556 0.86 MRGPRX4 (0.67) MRGPRX4MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116571189-B Preparation process of 5- (2-chloro-4- (trifluoromethyl) phenoxy) -2-nitrobenzoic acid 江苏长青农化南通有限公司 2024-04-02 CN claimed
CN-115997767-A Herbicide for weed control plant protection and time precise control method 贵州省生物技术研究所(贵州省生物技术重点实验室、贵州省马铃薯研究所、贵州省食品加工研究所) 2023-04-25 CN claimed
CN-116571189-B Preparation process of 5- (2-chloro-4- (trifluoromethyl) phenoxy) -2-nitrobenzoic acid 江苏长青农化南通有限公司 2024-04-02 CN disclosed
CN-117043154-A GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof 卡莫特医疗有限公司 2023-11-10 CN disclosed
CN-116571189-A Preparation process of 5- (2-chloro-4- (trifluoromethyl) phenoxy) -2-nitrobenzoic acid 江苏长青农化南通有限公司 2023-08-11 CN disclosed
CN-115997767-A Herbicide for weed control plant protection and time precise control method 贵州省生物技术研究所(贵州省生物技术重点实验室、贵州省马铃薯研究所、贵州省食品加工研究所) 2023-04-25 CN disclosed