SCHEMBL30278573

SCHEMBL30278573

Clc1ccc(Sc2ccc(Cl)cc2Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
PDE7A Q13946 7/20 0.42
PDE7B Q9NP56 5/20 0.42
RHEB Q15382 4/20 0.42
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
PDE4B Q07343 1/20 0.39
PDE4D Q08499 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24871310 1.00 MEN1 (0.53) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL25177150 0.88 PDE7A (0.54) MEN1KMT2APDE7APDE7BL3MBTL1
SCHEMBL3537628 0.85 HTR1A (0.50) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL3541411 0.85 MEN1 (0.47) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL3542952 0.81 MEN1 (0.43) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL3547807 0.79 SLC6A4 (0.50) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL6932304 0.78 PDE7A (0.39) MEN1KMT2AMAPTHPGDCYP1A2
SCHEMBL15207464 0.76 MEN1 (0.55) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL2850872 0.75 HPGD (0.58) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL11757959 0.75 MEN1 (0.53) MEN1KMT2AKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082119-B Compound for organic electronic element, organic electronic element using the same, and electronic device using the same 德山新勒克斯有限公司 2024-10-01 CN disclosed
CN-116162015-B Compound for organic electronic element, organic electronic element using the same, and electronic device using the same 德山新勒克斯有限公司 2024-03-26 CN disclosed
CN-116162015-A Compound for organic electronic element, organic electronic element using the same, and electronic device using the same 德山新勒克斯有限公司 2023-05-26 CN disclosed
CN-116082119-A Compound for organic electronic element, organic electronic element using the same, and electronic device using the same 德山新勒克斯有限公司 2023-05-09 CN disclosed
CN-115776979-A Compound for organic electronic element, organic electronic element using the same, and electronic device thereof 德山新勒克斯有限公司 2023-03-10 CN disclosed