Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952071 | 1.00 | TSHR (0.52) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL21951993 | 0.86 | TSHR (0.65) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL21952063 | 0.80 | TSHR (0.62) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL30278746 | 0.80 | TSHR (0.51) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL21952088 | 0.80 | TSHR (0.51) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL30278759 | 0.80 | TSHR (0.70) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL21952015 | 0.80 | TSHR (0.70) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL29798204 | 0.76 | TSHR (0.61) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL21952017 | 0.76 | TSHR (0.65) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA | |
| SCHEMBL21952051 | 0.76 | TSHR (0.65) | TSHRAPOBEC3AAPOBEC3GALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-B | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2025-03-04 | — | — | CN | disclosed |
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |