Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21951990 | 1.00 | HPGD (0.50) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21952070 | 0.82 | MEN1 (0.61) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL31396394 | 0.82 | MEN1 (0.61) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28681663 | 0.77 | HPGD (0.56) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21952057 | 0.72 | MAPK1 (0.54) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL21952075 | 0.70 | MEN1 (0.65) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL31396071 | 0.70 | MEN1 (0.65) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL31396404 | 0.70 | RECQL (0.48) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL22010389 | 0.70 | HPGD (0.69) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL24210198 | 0.70 | KDM4E (0.64) | HPGDMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-B | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2025-03-04 | — | — | CN | disclosed |
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |