Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17374412 | 0.86 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL17374415 | 0.86 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL4088870 | 0.79 | TP53 (0.46) | ALDH1A1SMN1; SMN2MAPTPKMNPSR1 | |
| SCHEMBL4088867 | 0.79 | TP53 (0.46) | ALDH1A1SMN1; SMN2MAPTPKMNPSR1 | |
| SCHEMBL10476737 | 0.79 | TP53 (0.46) | ALDH1A1SMN1; SMN2MAPTPKMNPSR1 | |
| SCHEMBL765277 | 0.79 | TP53 (0.46) | ALDH1A1SMN1; SMN2MAPTPKMNPSR1 | |
| SCHEMBL18299213 | 0.79 | MAPT (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL5006280 | 0.79 | MAPT (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1307950 | 0.79 | MAPT (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1298246 | 0.78 | MAPT (0.50) | ALDH1A1KMT2AMEN1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299386-A1 | Novel imidazole derivatives having protein kinase inhibitory activity and uses thereof | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2024-09-12 | — | — | US | disclosed |
| WO-2023022463-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON PROTEIN PHOSPHORELATION AND USE THEREOF | 한양대학교 에리카산학협력단 | 2023-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299386-A1 | Novel imidazole derivatives having protein kinase inhibitory activity and uses thereof | MAPKAPK3, MAPK3, MAP2K3 | ALDH1A1 4403/4885KMT2A 2612/4885MEN1 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.