Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129825 | 1.00 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL23978723 | 0.91 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL30279426 | 0.91 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL23978808 | 0.90 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL30279365 | 0.90 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL30279364 | 0.90 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL23978860 | 0.88 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL10129824 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2PKMLMNAKMT2A | |
| SCHEMBL30279449 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2PKMLMNAKMT2A | |
| SCHEMBL23978743 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2PKMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |