Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978743 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL30279364 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL30279365 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL23978808 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL23978723 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL30279426 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1PKMLMNAMAPT | |
| SCHEMBL23978844 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1PKMLMNAL3MBTL1 | |
| SCHEMBL30279391 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAL3MBTL1NCOA3 | |
| SCHEMBL23978742 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAL3MBTL1NCOA3 | |
| SCHEMBL10129825 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1PKMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |