Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975741 | 1.00 | THRB (0.51) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL30279640 | 1.00 | THRB (0.51) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL28965217 | 0.88 | THRB (0.52) | THRBNPC1RXFP1TP53MAPT | |
| SCHEMBL25633311 | 0.85 | THRB (0.48) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL30279650 | 0.85 | THRB (0.48) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL30279639 | 0.85 | THRB (0.52) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL25633303 | 0.85 | THRB (0.52) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL23975546 | 0.85 | THRB (0.54) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL30279652 | 0.85 | THRB (0.54) | THRBNPC1RXFP1TP53KDM4E | |
| SCHEMBL30279648 | 0.83 | TSHR (0.53) | THRBNPC1RXFP1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143192-A1 | NEW TRIAZINOINDOLE COMPOUNDS | JANSSEN Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |