Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742544 | 1.00 | CDK2 (0.53) | CDK2CSNK2A1MAPKAPK2CSNK2A2BCL6 | |
| SCHEMBL30279912 | 0.82 | KDM4E (0.43) | CDK2CSNK2A1CSNK2A2 | |
| SCHEMBL30279953 | 0.81 | CDK2 (0.51) | CDK2CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL19742461 | 0.81 | CDK2 (0.51) | CDK2CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL19742519 | 0.80 | CDK2 (0.47) | CDK2CSNK2A1MAPKAPK2CSNK2A2BCL6 | |
| SCHEMBL30279917 | 0.80 | CDK2 (0.57) | CDK2CSNK2A1MAPKAPK2CSNK2A2BCL6 | |
| SCHEMBL19742549 | 0.80 | CDK2 (0.57) | CDK2CSNK2A1MAPKAPK2CSNK2A2BCL6 | |
| SCHEMBL19742795 | 0.76 | CDK2 (0.50) | CDK2CSNK2A1MAPKAPK2CSNK2A2BCL6 | |
| SCHEMBL29355749 | 0.76 | CDK2 (0.46) | CDK2CSNK2A1CSNK2A2KCNH2HIPK1 | |
| SCHEMBL19742533 | 0.72 | KCNH2 (0.50) | CDK2CSNK2A1CSNK2A2KCNH2HIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |