Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742461 | 1.00 | CDK2 (0.51) | CDK2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL30279899 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL19742544 | 0.81 | CDK2 (0.53) | CDK2CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL30279929 | 0.81 | CDK2 (0.53) | CDK2CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL19742549 | 0.78 | CDK2 (0.57) | CDK2ALDH1A1CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL30279917 | 0.78 | CDK2 (0.57) | CDK2ALDH1A1CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL19742519 | 0.77 | CDK2 (0.47) | CDK2ALDH1A1CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL19742795 | 0.75 | CDK2 (0.50) | CDK2CSNK2A1MAPKAPK2CSNK2A2 | |
| SCHEMBL19742687 | 0.73 | KCNH2 (0.49) | CDK2CSNK2A1CSNK2A2 | |
| SCHEMBL29355749 | 0.72 | CDK2 (0.46) | CDK2ALDH1A1CSNK2A1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |