Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.41 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534906 | 0.86 | DGAT1 (0.41) | DGAT1PRPS1NPC1KDM4E | |
| SCHEMBL24344845 | 0.86 | DGAT1 (0.41) | DGAT1PRPS1NPC1KDM4E | |
| SCHEMBL15825447 | 0.82 | DGAT1 (0.40) | DGAT1PRPS1NPC1 | |
| SCHEMBL30280225 | 0.81 | DGAT1 (0.34) | DGAT1NPC1KDM4EALDH1A1 | |
| SCHEMBL30279997 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL25349668 | 0.81 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL22326078 | 0.80 | DGAT1 (0.35) | DGAT1NPC1 | |
| SCHEMBL21458046 | 0.79 | DGAT1 (0.37) | DGAT1NPC1ALDH1A1 | |
| SCHEMBL31550975 | 0.78 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL30280270 | 0.78 | DGAT1 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408837-A1 | BENZIMIDAZOLE AND AZABENZIMIDAZOLE IL-17 INHIBITOR COMPOUNDS | JANSSEN Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023049885-A1 | BENZIMIDAZOLE AND AZABENZIMIDAZOLE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |