Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280784 | 0.87 | HCAR2 (0.36) | HCAR2POLBTDP1L3MBTL1PTGER4 | |
| SCHEMBL30280911 | 0.81 | AKR1C2 (0.35) | HCAR2FASN | |
| SCHEMBL12489429 | 0.79 | FASN (0.39) | HCAR2FASNPOLBTDP1L3MBTL1 | |
| SCHEMBL30280993 | 0.78 | AKR1C2 (0.37) | HCAR2PTGER4 | |
| SCHEMBL12488318 | 0.77 | HCAR2 (0.37) | HCAR2FASNPOLBTDP1L3MBTL1 | |
| SCHEMBL12489139 | 0.76 | FASN (0.38) | HCAR2FASNPOLBTDP1L3MBTL1 | |
| SCHEMBL12489130 | 0.76 | FASN (0.38) | HCAR2FASNPOLBTDP1L3MBTL1 | |
| SCHEMBL30280695 | 0.76 | HCAR2 (0.34) | HCAR2FASNPOLB | |
| SCHEMBL12488381 | 0.74 | FASN (0.39) | HCAR2FASNPOLBTDP1L3MBTL1 | |
| SCHEMBL12489448 | 0.68 | FASN (0.39) | HCAR2FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |