Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 8/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 8/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280993 | 0.86 | AKR1C2 (0.37) | AKR1C2AKR1C1HCAR2PTGESPRKAB2 | |
| SCHEMBL30280784 | 0.81 | HCAR2 (0.36) | HCAR2 | |
| SCHEMBL30280666 | 0.81 | HCAR2 (0.38) | HCAR2FASN | |
| SCHEMBL12488381 | 0.78 | FASN (0.39) | HCAR2PTGESPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30280695 | 0.75 | HCAR2 (0.34) | AKR1C2AKR1C1HCAR2FASNMAPT | |
| SCHEMBL12489448 | 0.74 | FASN (0.39) | HCAR2PTGESPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL12488318 | 0.74 | HCAR2 (0.37) | HCAR2FASN | |
| SCHEMBL12489139 | 0.73 | FASN (0.38) | HCAR2PTGESFASN | |
| SCHEMBL12489130 | 0.73 | FASN (0.38) | HCAR2PTGESFASN | |
| SCHEMBL12489429 | 0.71 | FASN (0.39) | HCAR2FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |