SCHEMBL30280693

SCHEMBL30280693

CCc1cc(C)c(C(=O)N2CCC(F)(c3ncccc3C#N)CC2)cc1N

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12686746 0.81 FASN (0.65) FASN
SCHEMBL30281018 0.79 FASN (0.45) FASN
SCHEMBL30280979 0.77 FASN (0.42) FASN
SCHEMBL12489387 0.73 FASN (0.60) FASN
SCHEMBL23367719 0.70 FASN (0.50) FASN
SCHEMBL12487926 0.70 FASN (0.58) FASN
SCHEMBL30280945 0.70 FASN (0.58) FASN
SCHEMBL29981002 0.69 FASN (0.60) FASN
SCHEMBL18432359 0.68 FASN (0.69) FASN
SCHEMBL20156499 0.68 FASN (0.60) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139138-A Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-05-23 — — CN disclosed
CN-110177551-B Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-02-17 — — CN disclosed
Send feedback