Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12588621 | 0.95 | TSHR (0.41) | TSHRHPGDLPAR5CYP3A4ALDH1A1 | |
| SCHEMBL459135 | 0.90 | TSHR (0.42) | TSHRHPGDLPAR5USP2CYP3A4 | |
| SCHEMBL26310564 | 0.89 | TSHR (0.36) | TSHRHPGDUSP2CYP3A4CYP1A2 | |
| SCHEMBL15249282 | 0.88 | TSHR (0.39) | TSHRHPGDLPAR5USP2HTT | |
| SCHEMBL411497 | 0.88 | TSHR (0.41) | TSHRHPGDLPAR5CYP3A4ALDH1A1 | |
| SCHEMBL13584916 | 0.87 | LPAR5 (0.35) | LPAR5USP2HTTCYP3A4CYP1A2 | |
| SCHEMBL30280726 | 0.84 | TSHR (0.40) | TSHRHPGDCYP3A4ALDH1A1TP53 | |
| SCHEMBL12131518 | 0.84 | TSHR (0.41) | TSHRHPGDLPAR5CYP3A4ALDH1A1 | |
| SCHEMBL14962089 | 0.83 | TSHR (0.40) | TSHRLPAR5USP2HTTCYP3A4 | |
| SCHEMBL25563788 | 0.83 | TSHR (0.40) | TSHRLPAR5USP2HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230074745-A1 | COATING AGENT AND MEDICAL MATERIAL USING SAME | TORAY INDUSTRIES, INC. (JP) | 2023-03-09 | — | — | US | disclosed |