Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17669997 | 1.00 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1PDK2PDK4KDM4E | |
| SCHEMBL30410057 | 0.94 | PDK2 (0.52) | HSP90AA1HSP90AB1PDK2PDK4KDM4E | |
| SCHEMBL13645911 | 0.87 | HTR2C (0.56) | HSP90AA1HSP90AB1PDK2PDK4 | |
| Hydrochloric Acid SCHEMBL3869528 | 0.85 | HTR2C (0.57) | HSP90AA1HSP90AB1PDK2PDK4 | |
| SCHEMBL15648565 | 0.85 | KDM4E (0.51) | PDK2PDK4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7598114 | 0.82 | KDM4E (0.55) | PDK2PDK4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL21932852 | 0.81 | KDM4E (0.48) | PDK2PDK4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27201790 | 0.81 | PDK2 (0.49) | PDK2PDK4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1793340 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL30280727 | 0.81 | PTGER4 (0.41) | HSP90AA1HSP90AB1PDK2PDK4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |