Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280992 | 0.87 | PTGER4 (0.43) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL30280880 | 0.85 | PTGER4 (0.41) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL30280983 | 0.84 | PTGER4 (0.41) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL30280908 | 0.84 | PTGER4 (0.41) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL17669997 | 0.81 | HSP90AA1 (0.48) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL30280770 | 0.81 | HSP90AA1 (0.48) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL30281122 | 0.79 | PTGER4 (0.43) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL30281005 | 0.78 | ALDH1A1 (0.43) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL8580491 | 0.75 | CMA1 (0.40) | PTGER4PDK2PDK4HSP90AA1HSP90AB1 | |
| SCHEMBL15957674 | 0.75 | KDM4E (0.42) | PTGER4PDK2PDK4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |