Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 17/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 11/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.33 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280937 | 0.97 | CAMKK2 (0.41) | CAMKK2CAMKK1KDM5AKDM5BSGK1 | |
| SCHEMBL30280872 | 0.86 | PDK2 (0.39) | CAMKK2 | |
| SCHEMBL30280777 | 0.85 | CAMKK2 (0.36) | CAMKK2CAMKK1HCAR2KDM5AKDM5B | |
| SCHEMBL30280839 | 0.83 | CAMKK2 (0.41) | CAMKK2CAMKK1HCAR2KDM5AKDM5B | |
| SCHEMBL30281022 | 0.81 | CAMKK2 (0.40) | CAMKK2CAMKK1HCAR2SGK1AURKA | |
| SCHEMBL12488371 | 0.79 | FASN (0.41) | — | |
| SCHEMBL30280875 | 0.77 | FASN (0.45) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL30281015 | 0.76 | FASN (0.34) | CAMKK2CAMKK1GPR35 | |
| SCHEMBL12489277 | 0.76 | FASN (0.39) | CAMKK2CAMKK1KDM5AKDM5B | |
| SCHEMBL30281063 | 0.76 | CAMKK2 (0.35) | CAMKK2CAMKK1HCAR2KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |