Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280874 | 0.95 | HSD17B10 (0.37) | HSD17B10KDM4EALDH1A1CA12CA1 | |
| SCHEMBL22696462 | 0.77 | HSD17B10 (0.36) | HSD17B10KDM4EALDH1A1CA12CA1 | |
| SCHEMBL30280735 | 0.77 | MAPT (0.37) | POLBMAPT | |
| SCHEMBL28876061 | 0.77 | MAPT (0.37) | POLBMAPT | |
| SCHEMBL27507003 | 0.77 | KDM4E (0.47) | HSD17B10KDM4EALDH1A1CA12CA1 | |
| SCHEMBL30280981 | 0.76 | PDK2 (0.37) | KDM4EALDH1A1LMNAPOLBTSHR | |
| SCHEMBL30281000 | 0.76 | HSD17B10 (0.39) | HSD17B10KDM4EALDH1A1CA12CA1 | |
| SCHEMBL30280863 | 0.75 | DRD2 (0.32) | HSD17B10KDM4EALDH1A1TSHRMAPT | |
| SCHEMBL12487977 | 0.74 | PDK2 (0.38) | HSD17B10KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL30280912 | 0.72 | DRD2 (0.47) | HSD17B10KDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |