Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.31 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600392 | 0.68 | NPC1 (0.44) | NPC1 | |
| SCHEMBL30281268 | 0.67 | SMN1; SMN2 (0.36) | TEAD1TEAD4TEAD2 | |
| SCHEMBL16856709 | 0.66 | NPC1 (0.43) | NPC1 | |
| SCHEMBL31054928 | 0.66 | — | — | |
| SCHEMBL31054856 | 0.66 | — | — | |
| SCHEMBL30281156 | 0.62 | — | — | |
| SCHEMBL30444863 | 0.60 | HTT (0.39) | — | |
| SCHEMBL28976609 | 0.58 | TEAD1 (0.36) | TEAD1TEAD4TEAD2 | |
| SCHEMBL13267497 | 0.56 | TSHR (0.48) | — | |
| SCHEMBL25702335 | 0.56 | NPC1 (0.36) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |