Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17114341 | 0.99 | RIPK1 (0.63) | RIPK1NR1H2NR1H3HSD11B1PRMT5 | |
| SCHEMBL24365782 | 0.99 | RIPK1 (0.63) | RIPK1NR1H2NR1H3HSD11B1PRMT5 | |
| SCHEMBL7469150 | 0.99 | RIPK1 (0.63) | RIPK1NR1H2NR1H3HSD11B1PRMT5 | |
| Water SCHEMBL27902502 | 0.97 | RIPK1 (0.62) | RIPK1NR1H2NR1H3HSD11B1PRMT5 | |
| SCHEMBL27830000 | 0.95 | RIPK1 (0.59) | RIPK1NR1H2NR1H3HSD11B1PRMT5 | |
| SCHEMBL6960066 | 0.94 | RIPK1 (0.69) | RIPK1NR1H2NR1H3GPR119HCRTR2 | |
| SCHEMBL18642714 | 0.94 | RIPK1 (0.69) | RIPK1NR1H2NR1H3GPR119HCRTR2 | |
| SCHEMBL28193156 | 0.92 | RIPK1 (0.56) | RIPK1NR1H2NR1H3HSD11B1PRMT5 | |
| SCHEMBL27504373 | 0.90 | RIPK1 (0.66) | RIPK1NR1H2NR1H3GPR119HCRTR2 | |
| SCHEMBL4967031 | 0.86 | RIPK1 (0.49) | RIPK1NR1H2NR1H3TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |