Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.73 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12488997 | 1.00 | SIGMAR1 (0.73) | SIGMAR1AVPR1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4216497 | 0.86 | SIGMAR1 (0.74) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2359969 | 0.85 | SIGMAR1 (0.73) | SIGMAR1AVPR1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL747866 | 0.84 | SIGMAR1 (1.00) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL6314091 | 0.83 | SIGMAR1 (0.97) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL20955046 | 0.81 | SIGMAR1 (0.67) | SIGMAR1AVPR1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3839594 | 0.79 | AVPR1A (0.60) | SIGMAR1AVPR1ADRD2 | |
| SCHEMBL4214518 | 0.79 | SIGMAR1 (0.74) | SIGMAR1AVPR1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL16836276 | 0.79 | SIGMAR1 (0.66) | SIGMAR1AVPR1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11831890 | 0.79 | SIGMAR1 (0.66) | SIGMAR1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |