Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319770 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL5283767 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL162645 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL113627 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL3161688 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL3129966 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL10921948 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL318331 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL22653488 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 | |
| SCHEMBL63740 | 1.00 | LMNA (0.55) | LMNAGPR84SPHK1FFAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216889-A1 | PROLONGED EFFECT DISINFECTANT CLEANSER | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 2010-08-26 | — | — | US | disclosed |
| US-4073775-A | Powder coating composition | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-02-14 | — | — | US | disclosed |