E968

E968

SCHEMBL3028252

O=C1CCCCCO1.OC[C@@H](O)[C@@H](O)CO

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.61
CA9 Q16790 1/20 0.61
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
FKBP4 Q02790 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E968 SCHEMBL3028249 1.00 CA1 (0.61) CA1CA9ALDH1A1LMNATP53
Xylitol SCHEMBL3070130 0.93 CA1 (0.57) CA1CA9ALDH1A1LMNATP53
Mannitol SCHEMBL28217079 0.93 CA1 (0.57) CA1CA9ALDH1A1LMNATP53
Adonitol SCHEMBL28232574 0.93 CA1 (0.57) CA1CA9ALDH1A1LMNATP53
Glycerin SCHEMBL25397611 0.89 CA1 (0.61) CA1CA9ALDH1A1LMNATP53
Propylene Glycol SCHEMBL27838292 0.87 CA1 (0.59) CA1CA9ALDH1A1LMNATP53
Propylene Glycol SCHEMBL28251397 0.87 CA1 (0.59) CA1CA9ALDH1A1LMNATP53
Propylene Glycol SCHEMBL28283981 0.87 CA1 (0.59) CA1CA9ALDH1A1LMNATP53
Glycerin SCHEMBL28537060 0.86 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
SCHEMBL28990814 0.86 CA1 (0.76) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8867960-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2014-10-21 US disclosed
EP-2535774-B1 Image bearing drum, image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2014-07-30 EP disclosed
US-20130243484-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
EP-2535774-A1 Image bearing drum, image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2012-12-19 EP disclosed
US-7846635-B2 Image forming apparatus, image forming method and process cartridge RICOH COMPANY, LTD. (JP) 2010-12-07 US disclosed
US-7785762-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-08-31 US disclosed
US-20100196049-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2010-08-05 US disclosed
US-7670743-B2 Image forming method RICOH COMPANY, LTD. (JP) 2010-03-02 US disclosed
US-20090269103-A1 Photoreceptor, process cartridge and image forming apparatus RICOH COMPANY, LTD. 2009-10-29 US disclosed
US-7537872-B2 Image bearing member with charge blocking layer and moire prevention layer, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2009-05-26 US disclosed
US-20080145778-A1 IMAGE FORMING APPARATUS SOCKET MOBILE, INC. FKA SOCKET COMMUNICATIONS, INC. 2008-06-19 US disclosed
US-20080031653-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-02-07 US disclosed
US-20060240346-A1 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2006-10-26 US disclosed
US-20060197823-A1 Image forming apparatus RICOH COMPANY, LTD. (JP) 2006-09-07 US disclosed