Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adonitol SCHEMBL28232574 | 1.00 | CA1 (0.57) | CA1CA9LMNAALDH1A1TP53 | |
| Mannitol SCHEMBL28217079 | 0.96 | CA1 (0.57) | CA1CA9LMNAALDH1A1TP53 | |
| E968 SCHEMBL3028252 | 0.93 | CA1 (0.61) | CA1CA9LMNAALDH1A1TP53 | |
| E968 SCHEMBL3028249 | 0.93 | CA1 (0.61) | CA1CA9LMNAALDH1A1TP53 | |
| Gluconic Acid SCHEMBL27667050 | 0.86 | PDE4A (0.54) | CA1CA9LMNATSHRL3MBTL1 | |
| Demannose SCHEMBL27667049 | 0.86 | CA1 (0.46) | CA1CA9LMNAL3MBTL1TDP1 | |
| Gluconic Acid SCHEMBL2802087 | 0.86 | PDE4A (0.54) | CA1CA9LMNATSHRL3MBTL1 | |
| Glycerin SCHEMBL25397611 | 0.85 | CA1 (0.61) | CA1CA9LMNAALDH1A1TP53 | |
| Propylene Glycol SCHEMBL28283981 | 0.84 | CA1 (0.59) | CA1CA9LMNAALDH1A1TP53 | |
| Propylene Glycol SCHEMBL27838292 | 0.84 | CA1 (0.59) | CA1CA9LMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9186422-B2 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PATHAK HOLDINGS LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-20120308481-A1 | RADIO-OPAQUE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND METHODS OF THEIR SYNTHESIS AND USE | PATHAK HOLDINGS LLC (US) | 2012-12-06 | — | — | US | disclosed |
| US-8273327-B2 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PATHAK HOLDINGS, LLC (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100290995-A1 | RADIO-OPAQUE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND METHODS OF THEIR SYNTHESIS AND USE | PATHAK HOLDINGS LLC | 2010-11-18 | — | — | US | disclosed |
| US-7790141-B2 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PATHAK HOLDINGS, LLC (US) | 2010-09-07 | — | — | US | disclosed |
| US-20050036946-A1 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PATHAK HOLDINGS, LLC | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120308481-A1 | RADIO-OPAQUE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND METHODS OF THEIR SYNTHESIS AND USE | PLOD3, IK, SON | CA1 2512/4885CA9 2698/4885LMNA 719/4885 |
| US-20100290995-A1 | RADIO-OPAQUE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND METHODS OF THEIR SYNTHESIS AND USE | PLOD3, IK, SON | CA1 2512/4885CA9 2698/4885LMNA 719/4885 |
| US-20050036946-A1 | Radio-opaque compounds, compositions containing same and methods of their synthesis and use | PLOD3, IK, SON | CA1 2512/4885CA9 2698/4885LMNA 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.