Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30282924 | 1.00 | CMA1 (0.45) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL25045468 | 0.78 | CMA1 (0.47) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL30437375 | 0.75 | CMA1 (0.47) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL31506511 | 0.74 | CMA1 (0.46) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL17360659 | 0.73 | CMA1 (0.56) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL20833765 | 0.73 | CMA1 (0.45) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL34468997 | 0.73 | CMA1 (0.45) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL34469158 | 0.73 | CMA1 (0.45) | CMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL17360678 | 0.70 | EHMT2 (0.61) | CMA1MEN1KMT2AGSK3AGSK3B | |
| SCHEMBL17360668 | 0.70 | CMA1 (0.56) | CMA1HCRTR1HCRTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |