Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317639 | 0.81 | SIGMAR1 (0.52) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL22518782 | 0.80 | TSHR (0.64) | CMA1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL14175552 | 0.77 | HCRTR1 (0.48) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL27224947 | 0.77 | HCRTR1 (0.48) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL31506511 | 0.76 | CMA1 (0.46) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL23706942 | 0.75 | CMA1 (0.45) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL34469158 | 0.75 | CMA1 (0.45) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL20833765 | 0.75 | CMA1 (0.45) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL23706943 | 0.75 | CYP3A4 (0.54) | CMA1HCRTR1HCRTR2GSK3AGSK3B | |
| SCHEMBL34468997 | 0.75 | CMA1 (0.45) | CMA1HCRTR1HCRTR2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |