Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 17/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24154771 | 1.00 | MAT2A (0.54) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25262199 | 0.86 | MAT2A (0.53) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30319982 | 0.86 | MAT2A (0.53) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30277843 | 0.85 | MAT2A (0.57) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24109555 | 0.85 | MAT2A (0.57) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25259207 | 0.85 | MAT2A (0.53) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29893575 | 0.84 | MAT2A (0.71) | MAT2A | |
| SCHEMBL24109554 | 0.84 | MAT2A (0.71) | MAT2A | |
| SCHEMBL24109624 | 0.80 | MAT2A (0.69) | MAT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28889269 | 0.74 | MAT2A (0.58) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |