Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 19/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372911 | 1.00 | TRPV4 (0.70) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL2373098 | 0.96 | TRPV4 (0.70) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL30284319 | 0.94 | TRPV4 (0.68) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL2399242 | 0.94 | TRPV4 (0.68) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL6845474 | 0.94 | TRPV4 (0.70) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL30284377 | 0.94 | TRPV4 (0.70) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL2372313 | 0.93 | TRPV4 (0.65) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL30283834 | 0.93 | TRPV4 (0.65) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL2372968 | 0.92 | TRPV4 (0.72) | TRPV4NR1I2TACR2TACR3KCNH2 | |
| SCHEMBL2372421 | 0.92 | TRPV4 (0.72) | TRPV4NR1I2TACR2TACR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776890-A | TRPV4 inhibitors as therapeutic agents for eye diseases | 拉夸里亚创药株式会社 | 2023-03-10 | — | — | CN | disclosed |