Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD2 | P13995 | 7/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464166 | 1.00 | MTHFD2 (0.39) | MTHFD2PTGDR2MC4R | |
| SCHEMBL23972440 | 1.00 | MTHFD2 (0.39) | MTHFD2PTGDR2MC4R | |
| SCHEMBL31407022 | 1.00 | MTHFD2 (0.39) | MTHFD2PTGDR2MC4R | |
| SCHEMBL31407024 | 0.85 | MTHFD2 (0.44) | MTHFD2PTGDR2 | |
| SCHEMBL30283868 | 0.85 | MTHFD2 (0.44) | MTHFD2PTGDR2 | |
| SCHEMBL23973017 | 0.85 | MTHFD2 (0.44) | MTHFD2PTGDR2 | |
| SCHEMBL34464082 | 0.85 | MTHFD2 (0.44) | MTHFD2PTGDR2 | |
| SCHEMBL26672730 | 0.80 | MTHFD2 (0.42) | MTHFD2 | |
| SCHEMBL34464018 | 0.79 | MTHFD2 (0.42) | MTHFD2 | |
| SCHEMBL26672694 | 0.79 | MTHFD2 (0.42) | MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | claimed |
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115776890-A | TRPV4 inhibitors as therapeutic agents for eye diseases | 拉夸里亚创药株式会社 | 2023-03-10 | — | — | CN | disclosed |