Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.46 |
| ▸ | XIAP | P98170 | 2/20 | 0.45 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | DPP3 | Q9NY33 | 2/20 | 0.42 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031622 | 0.91 | CALCRL (0.47) | CALCRLXIAPMLXCAPN1SLC6A2 | |
| SCHEMBL30674926 | 0.90 | XIAP (0.47) | XIAPMLXCAPN1CTSBDPP3 | |
| SCHEMBL29695544 | 0.88 | CALCRL (0.58) | CALCRLSLC6A2DPP3RAMP1REN | |
| SCHEMBL30432749 | 0.87 | CAPN1 (0.51) | CALCRLXIAPMLXCAPN1SLC6A2 | |
| SCHEMBL30518982 | 0.86 | CAPN1 (0.53) | CALCRLXIAPCAPN1CTSBRAMP1 | |
| SCHEMBL29630498 | 0.85 | CAPN1 (0.51) | XIAPCAPN1SLC6A2CTSBDPP3 | |
| SCHEMBL29423396 | 0.85 | ACE (0.43) | CALCRLXIAPMLXREN | |
| SCHEMBL31124672 | 0.85 | SLC6A2 (0.60) | CALCRLSLC6A2DPP3RAMP1REN | |
| SCHEMBL29630809 | 0.85 | CAPN1 (0.45) | XIAPMLXCAPN1SLC6A2CTSB | |
| SCHEMBL29591830 | 0.83 | CAPN1 (0.47) | CALCRLXIAPMLXCAPN1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476732-B | Trispecific and/or trivalent binding proteins | 赛诺菲 | 2024-03-22 | — | — | CN | disclosed |
| CN-117069855-A | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection | 赛诺菲 | 2023-11-17 | — | — | CN | disclosed |
| CN-116789841-A | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection | 赛诺菲 | 2023-09-22 | — | — | CN | disclosed |
| CN-116675776-A | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection | 赛诺菲 | 2023-09-01 | — | — | CN | disclosed |
| CN-109311966-B | Trispecific and/or trivalent binding proteins for use in the prevention or treatment of HIV infection | 赛诺菲 | 2023-03-10 | — | — | CN | disclosed |