Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 5/20 | 0.47 |
| ▸ | XIAP | P98170 | 2/20 | 0.46 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630809 | 0.92 | CAPN1 (0.45) | XIAPMLXCAPN1CTSBGRB2 | |
| SCHEMBL30284980 | 0.91 | CALCRL (0.46) | CALCRLXIAPMLXCAPN1CTSB | |
| SCHEMBL29591830 | 0.90 | CAPN1 (0.47) | CALCRLXIAPMLXCAPN1CTSB | |
| SCHEMBL30518982 | 0.88 | CAPN1 (0.53) | CALCRLXIAPCAPN1CTSBRAMP1 | |
| SCHEMBL29630325 | 0.84 | XIAP (0.50) | CALCRLXIAPMLXCAPN1CTSB | |
| SCHEMBL30441489 | 0.84 | XIAP (0.52) | CALCRLXIAPMLXCAPN1CTSB | |
| SCHEMBL29630668 | 0.83 | CAPN1 (0.51) | CALCRLXIAPCAPN1CTSBSLC6A2 | |
| SCHEMBL30674926 | 0.83 | XIAP (0.47) | XIAPMLXCAPN1CTSBGRB2 | |
| SCHEMBL29630498 | 0.83 | CAPN1 (0.51) | XIAPCAPN1CTSBGRB2SLC6A2 | |
| SCHEMBL31031576 | 0.83 | CALCRL (0.67) | CALCRLRAMP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132725-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF INTRACRANIAL HEMORRHAGIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF INTRACRANIAL HEMORRHAGIC STROKE FROM ACUTE ISCHEMIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |