Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.69 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966135 | 1.00 | HDAC2 (1.00) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL28970473 | 0.87 | HDAC2 (0.76) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL11388948 | 0.83 | HDAC6 (0.78) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL28970478 | 0.83 | HDAC6 (0.78) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL24755152 | 0.82 | HDAC6 (1.00) | HDAC2HDAC6TLR7IRAK4GAA | |
| Chlorobenzene SCHEMBL28344826 | 0.81 | HDAC2 (0.67) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL3477450 | 0.80 | HDAC6 (0.67) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL13602299 | 0.79 | HDAC6 (0.70) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL28784680 | 0.79 | HDAC6 (0.74) | HDAC2HDAC6TLR7IRAK4GAA | |
| SCHEMBL11388201 | 0.79 | HDAC2 (0.65) | HDAC2HDAC6TLR7IRAK4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784986-A | HDAC6 inhibitor and preparation method and application thereof | 中国海洋大学 | 2023-03-14 | — | — | CN | disclosed |