Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.78 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.71 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.70 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | AXL | P30530 | 1/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24755152 | 0.87 | HDAC6 (1.00) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL11388948 | 0.86 | HDAC6 (0.78) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL31350948 | 0.84 | HDAC6 (0.70) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL1812154 | 0.84 | HDAC6 (0.70) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL11511135 | 0.84 | HDAC1 (0.74) | HDAC6HDAC2IRAK4TLR7ATM | |
| SCHEMBL2555278 | 0.84 | HPGD (0.72) | HDAC6IRAK4TLR7NPC1RAB9A | |
| SCHEMBL28784680 | 0.84 | HDAC6 (0.74) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL28601973 | 0.83 | HDAC6 (0.69) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL28966135 | 0.83 | HDAC2 (1.00) | HDAC6HDAC2IRAK4TLR7NPC1 | |
| SCHEMBL30285151 | 0.83 | HDAC2 (1.00) | HDAC6HDAC2IRAK4TLR7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806503-B | Selective histone deacetylase inhibitor and preparation method and application thereof | 中国海洋大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-115806503-A | Selective histone deacetylase inhibitor as well as preparation method and application thereof | 中国海洋大学 | 2023-03-17 | — | — | CN | disclosed |