SCHEMBL30285253

SCHEMBL30285253

N#CC(=O)c1cccnc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
ALDH1A1 P00352 4/20 0.59
APP P05067 1/20 0.59
GAA P10253 1/20 0.59
HCAR3 P49019 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59
F7 P08709 1/20 0.57
F3 P13726 1/20 0.57
SARM1 Q6SZW1 1/20 0.57
SIRT2 Q8IXJ6 1/20 0.57
SIRT6 Q8N6T7 1/20 0.57
SIRT1 Q96EB6 1/20 0.57
SIRT3 Q9NTG7 1/20 0.57
SIRT5 Q9NXA8 1/20 0.57
SIRT4 Q9Y6E7 1/20 0.57
HDAC1 Q13547 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
PLOD2 O00469 1/20 0.50
MAPT P10636 4/20 0.49
LMNA P02545 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27792527 1.00 POLB (0.59) POLBALDH1A1APPGAAHCAR3
SCHEMBL7120606 0.82 ALDH1A1 (0.61) POLBALDH1A1APPGAAHCAR3
SCHEMBL5632827 0.80 ALDH1A1 (0.59) POLBALDH1A1APPGAAHCAR3
SCHEMBL2928423 0.78 POLB (0.62) POLBALDH1A1APPGAAHCAR3
SCHEMBL2582102 0.78 ALDH1A1 (0.52) POLBALDH1A1APPGAAHCAR3
Niacin SCHEMBL23000891 0.77 ALDH1A1 (0.78) POLBALDH1A1APPGAAHCAR3
SCHEMBL7621786 0.77 POLB (0.56) POLBALDH1A1APPGAAHCAR3
SCHEMBL11255189 0.77 POLB (0.56) POLBALDH1A1APPGAAHCAR3
SCHEMBL7621795 0.77 POLB (0.56) POLBALDH1A1APPGAAHCAR3
Niacin SCHEMBL28282904 0.77 ALDH1A1 (0.78) POLBALDH1A1APPGAAHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113584538-B Graphene-nicotinic acid silver plating solution and preparation method thereof 南京清鹿新材料科技有限公司 2023-03-14 CN disclosed