Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.52 |
| ▸ | PARP1 | P09874 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131011 | 0.86 | BRAF (0.58) | MAPK1KDM1APRMT5WDR77ACVR1 | |
| SCHEMBL17785716 | 0.80 | KDM1A (0.48) | KDM1APRMT5WDR77PIM1PIM2 | |
| SCHEMBL23930158 | 0.78 | MEN1 (0.59) | PRMT5WDR77ACVR1EPHX2FLT3 | |
| SCHEMBL30285550 | 0.78 | MKNK1 (0.55) | PARP10PARP1MAPK1F7F3 | |
| SCHEMBL30285494 | 0.77 | PARP10 (0.54) | PARP10PARP1MAPK1F7F3 | |
| SCHEMBL21255300 | 0.77 | AXL (0.46) | KDM1APRMT5WDR77ACVR1EPHX2 | |
| SCHEMBL13820261 | 0.77 | PARP10 (0.76) | PARP10PARP1MAPK1F7F3 | |
| SCHEMBL5253621 | 0.75 | PARP10 (0.77) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL797294 | 0.74 | PARP10 (0.76) | PARP10PARP1F7F3MAPKAPK2 | |
| SCHEMBL25221604 | 0.74 | TNIK (0.53) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825656-B | Inhibitors of protein arginine methyltransferase 5 (PRMT 5), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2023-03-31 | — | — | CN | disclosed |