Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.54 |
| ▸ | PARP1 | P09874 | 6/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253621 | 0.80 | PARP10 (0.77) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL13820261 | 0.78 | PARP10 (0.76) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL797294 | 0.78 | PARP10 (0.76) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL13229196 | 0.78 | ASIC3 (0.40) | PARP10PARP11MAPKAPK2JAK2 | |
| SCHEMBL30285341 | 0.77 | PARP10 (0.52) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL26463093 | 0.77 | PARP10 (0.56) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL30494146 | 0.77 | PARP10 (0.56) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL31266571 | 0.74 | DRD2 (0.49) | PARP10PARP11JAK2 | |
| SCHEMBL15570967 | 0.74 | PRF1 (0.57) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL29892591 | 0.74 | PARP10 (0.71) | PARP10PARP11MAPKAPK2TDP2PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825656-B | Inhibitors of protein arginine methyltransferase 5 (PRMT 5), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2023-03-31 | — | — | CN | disclosed |