Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311951 | 1.00 | PRMT5 (0.42) | PRMT5WDR77FOLH1APPLTA4H | |
| SCHEMBL2671449 | 1.00 | PRMT5 (0.42) | PRMT5WDR77FOLH1APPLTA4H | |
| SCHEMBL5707160 | 1.00 | PRMT5 (0.42) | PRMT5WDR77FOLH1APPLTA4H | |
| SCHEMBL27529170 | 0.84 | EGFR (0.43) | PRMT5WDR77FOLH1APPSMN1; SMN2 | |
| SCHEMBL27529171 | 0.84 | EGFR (0.43) | PRMT5WDR77FOLH1APPSMN1; SMN2 | |
| SCHEMBL20431306 | 0.84 | PRKCA (0.40) | FOLH1APPLTA4HMAPK14SMN1; SMN2 | |
| SCHEMBL4428242 | 0.82 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL1311395 | 0.82 | ELANE (0.47) | PRMT5WDR77RAB9ACCR5 | |
| SCHEMBL11670452 | 0.82 | MEN1 (0.39) | PRMT5WDR77KMT2A | |
| SCHEMBL6897412 | 0.82 | FOLH1 (0.49) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | disclosed |