Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 5/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26125207 | 1.00 | MAP4K4 (0.58) | MAP4K4HDAC1CHRM4CHRM1PARP1 | |
| SCHEMBL26128841 | 1.00 | MAP4K4 (0.58) | MAP4K4HDAC1CHRM4CHRM1PARP1 | |
| SCHEMBL30546539 | 1.00 | MAP4K4 (0.58) | MAP4K4HDAC1CHRM4CHRM1PARP1 | |
| SCHEMBL21522485 | 0.87 | PARP1 (0.52) | MAP4K4HDAC1CHRM4CHRM1PARP1 | |
| SCHEMBL24963042 | 0.86 | GPR119 (0.58) | MAP4K4HDAC1CHRM4CHRM1GPR119 | |
| SCHEMBL24963653 | 0.86 | GPR119 (0.58) | MAP4K4HDAC1CHRM4CHRM1GPR119 | |
| SCHEMBL26125148 | 0.84 | PARP1 (0.58) | CHRM4CHRM1PARP1PARP2PANK3 | |
| SCHEMBL28982891 | 0.84 | PARP1 (0.58) | CHRM4CHRM1PARP1PARP2PANK3 | |
| SCHEMBL23560717 | 0.84 | MAP4K4 (0.52) | MAP4K4HDAC1CHRM4GPR119PIK3CD | |
| SCHEMBL23561132 | 0.84 | MAP4K4 (0.52) | MAP4K4HDAC1CHRM4GPR119PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4338737-A1 | PARP7 INHIBITOR AND USE THEREOF | Novostar Pharmaceuticals, Ltd. (CN) | 2024-03-20 | — | — | EP | disclosed |
| CN-115785074-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2023-03-14 | — | — | CN | disclosed |