Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27173051 | 0.91 | TIPARP (0.47) | ACACBTRPV4CHRM2CHRM1TIPARP | |
| SCHEMBL31381945 | 0.84 | TIPARP (0.41) | ACACBTRPV4CHRM2CHRM1TIPARP | |
| SCHEMBL29165859 | 0.83 | CHRM2 (0.53) | ACACBCHRM2CHRM1TIPARPHDAC3 | |
| SCHEMBL29165857 | 0.83 | CHRM2 (0.53) | ACACBCHRM2CHRM1TIPARPHDAC3 | |
| SCHEMBL27233782 | 0.83 | CHRM2 (0.53) | ACACBCHRM2CHRM1TIPARPHDAC3 | |
| SCHEMBL23727549 | 0.83 | CHRM2 (0.53) | ACACBCHRM2CHRM1TIPARPHDAC3 | |
| SCHEMBL23728082 | 0.83 | CHRM2 (0.53) | ACACBCHRM2CHRM1TIPARPHDAC3 | |
| SCHEMBL29165972 | 0.83 | CHRM2 (0.53) | ACACBCHRM2CHRM1TIPARPHDAC3 | |
| SCHEMBL26125453 | 0.82 | ACACB (0.42) | ACACBCHRM2CHRM1TIPARPSLC6A9 | |
| SCHEMBL24962970 | 0.82 | GPR119 (0.57) | ACACBTRPV4CHRM2CHRM1TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777099-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115785074-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2023-03-14 | — | — | CN | disclosed |