Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.53 |
| ▸ | IDH1 | O75874 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SGK1 | O00141 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354709 | 1.00 | SLC22A12 (0.53) | SLC22A12IDH1TP53SGK1PPARG | |
| SCHEMBL20340723 | 0.86 | SLC22A12 (0.50) | SLC22A12IDH1SGK1PPARGCYP3A4 | |
| SCHEMBL20355144 | 0.86 | SLC22A12 (0.58) | SLC22A12SGK1PPARGCYP3A4BRD4 | |
| SCHEMBL30286540 | 0.85 | SLC22A12 (0.41) | SLC22A12TP53SGK1BRD4NR3C1 | |
| SCHEMBL20354708 | 0.85 | SLC22A12 (0.41) | SLC22A12TP53SGK1BRD4NR3C1 | |
| SCHEMBL20339069 | 0.82 | MEN1 (0.42) | SLC22A12TP53BRD4NR3C1PGR | |
| SCHEMBL20339168 | 0.80 | SGK1 (0.47) | SLC22A12IDH1SGK1PPARGCYP3A4 | |
| SCHEMBL30286590 | 0.80 | IDH1 (0.46) | IDH1TP53BRD4ALPL | |
| SCHEMBL20354858 | 0.80 | IDH1 (0.46) | IDH1TP53BRD4ALPL | |
| SCHEMBL21545957 | 0.78 | CES1 (0.47) | IDH1SGK1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |