Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | SGK1 | O00141 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354708 | 1.00 | SLC22A12 (0.41) | SLC22A12NPC1TSHRACLYSGK1 | |
| SCHEMBL20339069 | 0.89 | MEN1 (0.42) | SLC22A12NPC1TSHRACLYWDR5 | |
| SCHEMBL20340337 | 0.88 | SLC22A12 (0.43) | SLC22A12ACLYSGK1CCR2 | |
| SCHEMBL20340338 | 0.86 | NPC1 (0.45) | NPC1TSHRACLYWDR5CCR2 | |
| SCHEMBL29903808 | 0.85 | WDR5 (0.43) | NPC1TSHRACLYWDR5CCR2 | |
| SCHEMBL30286555 | 0.85 | SLC22A12 (0.53) | SLC22A12SGK1TP53NR3C1PGR | |
| SCHEMBL26980267 | 0.85 | WDR5 (0.43) | NPC1TSHRACLYWDR5CCR2 | |
| SCHEMBL20354709 | 0.85 | SLC22A12 (0.53) | SLC22A12SGK1TP53NR3C1PGR | |
| SCHEMBL20340701 | 0.83 | ALDH1A1 (0.47) | NPC1TSHRACLYWDR5CCR2 | |
| SCHEMBL21545866 | 0.82 | SLC22A12 (0.50) | SLC22A12ACLYSGK1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |