Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.45 |
| ▸ | ACLY | P53396 | 3/20 | 0.44 |
| ▸ | SGK1 | O00141 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354710 | 1.00 | CCR2 (0.51) | CCR2KITSLC40A1ACLYSGK1 | |
| SCHEMBL30286514 | 0.94 | CCR2 (0.54) | CCR2KITACLYSGK1TSHR | |
| SCHEMBL21545856 | 0.94 | CCR2 (0.51) | CCR2KITSLC40A1ACLYSGK1 | |
| SCHEMBL20354690 | 0.94 | CCR2 (0.54) | CCR2KITACLYSGK1TSHR | |
| SCHEMBL29559629 | 0.94 | CCR2 (0.51) | CCR2KITSLC40A1ACLYSGK1 | |
| SCHEMBL20339172 | 0.92 | TSHR (0.46) | CCR2KITSLC40A1ACLYSGK1 | |
| SCHEMBL20354691 | 0.92 | CCR2 (0.46) | CCR2KITSLC40A1ACLYSGK1 | |
| SCHEMBL21569708 | 0.92 | SGK1 (0.43) | CCR2KITACLYSGK1MCL1 | |
| SCHEMBL20355128 | 0.92 | CCR2 (0.43) | CCR2KITSLC40A1ACLYSGK1 | |
| SCHEMBL20340322 | 0.92 | CCR2 (0.49) | CCR2KITSLC40A1ACLYSGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |