SCHEMBL30287602

SCHEMBL30287602

N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 6/20 0.58
▸ OPRD1 P41143 4/20 0.58
▸ SLC6A2 P23975 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30116353 0.97 OPRM1 (0.60) OPRM1OPRD1SLC6A2
SCHEMBL29390272 0.94 SLC6A2 (0.51) OPRM1OPRD1SLC6A2
SCHEMBL30631162 0.94 SLC6A2 (0.51) OPRM1OPRD1SLC6A2
SCHEMBL30116352 0.93 OPRM1 (0.54) OPRM1OPRD1SLC6A2
SCHEMBL30116349 0.93 OPRM1 (0.50) OPRM1OPRD1SLC6A2
SCHEMBL31683327 0.93 OPRM1 (0.50) OPRM1OPRD1SLC6A2
SCHEMBL30503062 0.92 OPRM1 (0.58) OPRM1OPRD1SLC6A2
SCHEMBL30503063 0.91 SLC6A2 (0.53) OPRM1OPRD1SLC6A2
SCHEMBL30533415 0.90 OPRM1 (0.53) OPRM1OPRD1SLC6A2
SCHEMBL30463400 0.89 OPRM1 (0.62) OPRM1OPRD1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116419765-A GLP-1/GIP dual agonists, long acting conjugates thereof and pharmaceutical compositions comprising the same 韩美药品株式会社 2023-07-11 — — CN disclosed
CN-116390769-A Pharmaceutical composition for preventing or treating lupus-related diseases comprising glucagon/GLP-1/GIP triple agonist or long-acting conjugate thereof 韩美药品株式会社 2023-07-04 — — CN disclosed
CN-116209475-A Therapeutic uses comprising a triple agonist long-acting conjugate or a combination of triple agonists 韩美药品株式会社 2023-06-02 — — CN disclosed
CN-115916238-A Hyperlipemia preventing or treating composition containing glucagon/GLP-l/GIP receptor triple agonist or conjugate thereof and use method thereof 韩美药品株式会社 2023-04-04 — — CN disclosed
CN-115811970-A Liquid formulations of long-acting conjugates of glucagon, GLP-1 and GIP triple agonists 韩美药品株式会社 2023-03-17 — — CN disclosed
CN-115803015-A Liquid formulations of long-acting conjugates of glucagon derivatives 韩美药品株式会社 2023-03-14 — — CN disclosed
CN-115776880-A Liquid preparation 韩美药品株式会社 2023-03-10 — — CN disclosed
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