Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633850 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL30634141 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL26633843 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL26764170 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL30288083 | 0.95 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL30634136 | 0.95 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL26633848 | 0.95 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL26633855 | 0.95 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL26764185 | 0.95 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL24011659 | 0.90 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146640-A2 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |