Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633889 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL26764178 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL26633894 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL30634186 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL26633708 | 0.93 | NPC1 (0.55) | SMN1; SMN2NPC1RAB9AKMT2ABLM | |
| SCHEMBL24011475 | 0.90 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL24011562 | 0.90 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL30288067 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AKMT2AMCHR1 | |
| SCHEMBL30634141 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AKMT2AMCHR1 | |
| SCHEMBL26764170 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AKMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843295-B | NAMPT modulators | 赛特凯恩蒂克公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115843295-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4146640-A2 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |