Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 5/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29089245 | 0.94 | DGKA (0.56) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL5709875 | 0.92 | EPHX2 (0.56) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL8413450 | 0.90 | MEN1 (0.52) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL28992205 | 0.90 | CYP1A2 (0.55) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL28326652 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL16814874 | 0.88 | DGKA (0.47) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL28878179 | 0.88 | DGKA (0.52) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL1516540 | 0.88 | DGKA (0.57) | SMN1; SMN2EPHX2DGKACYP1A2NAAA | |
| SCHEMBL11821128 | 0.87 | DGKA (0.59) | EPHX2DGKANAAADNM1 | |
| SCHEMBL11858057 | 0.87 | DGKA (0.59) | EPHX2DGKANAAADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809467-B | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-03-10 | — | — | CN | disclosed |