Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648979 | 0.77 | CCR1 (0.41) | — | |
| SCHEMBL5659171 | 0.76 | SNCA (0.40) | SNCAPDE3BPDE3ADAOABL1 | |
| SCHEMBL29626963 | 0.73 | HPGDS (0.36) | GRIN1GRIN2BGSK3AGSK3BCDK5 | |
| SCHEMBL3360121 | 0.73 | DAO (0.54) | SNCADAODDO | |
| SCHEMBL19126483 | 0.73 | SNCA (0.39) | SNCADAODDOAURKADAPK3 | |
| SCHEMBL6883082 | 0.72 | DAO (0.50) | PDE3BPDE3ADAODDOCDK5 | |
| SCHEMBL14977221 | 0.71 | NAMPT (0.40) | SNCAFGFR1KDR | |
| SCHEMBL2038785 | 0.71 | BRD4 (0.47) | SNCADAOJAK2KDR | |
| SCHEMBL29431210 | 0.71 | SNCA (0.42) | SNCA | |
| SCHEMBL20004561 | 0.71 | SNCA (0.42) | SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024085603-A1 | COMPOSITION FOR PREVENTING OR TREATING C-MYC-ASSOCIATED DISEASES THROUGH INHIBITION OF EXPRESSION OF UBIQUITIN-SPECIFIC PROTEASE 47 (USP47), AND USE THEREOF | 이화여자대학교 산학협력단 | 2024-04-25 | — | — | WO | disclosed |
| CN-116003405-A | Inhibitors of KRAS G12C and methods of use thereof | 美国安进公司 | 2023-04-25 | — | — | CN | disclosed |